Concept, Prototyping & Materials Formulation
CERAM’s unrivalled knowledge of material formulation and chemical composition analysis, and our understanding of the passivation of surfaces with coating technologies, make us uniquely placed to accelerate new product development projects, particularly with regard to controlled-release drugs.
We have:
- considerable knowledge of the chemical and physical properties of materials
- sophisticated surface and interface analysis instrumentation and many years experience of using surface and interface techniques to test and investigate pharmaceuticals and packaging.
Examples of some of the projects we have worked on:
- Investigation of the interaction of a steroid-based drug with rubber gasket material
- Investigation of a drug elution from coated stents by DSIMS
- Investigation of drug distribution in coated stents
- Characterisation of stents coated with drug-loaded PCL
- LSOM and DSIMS characterisation of coating on stents with different drug elution rates
- High resolution SIMS imaging of the distribution of drug active agent on lactose granules
- Characterisation of monodisperse polystyrene beads by XPS, ToFSIMS and SEM
- Surface characterisation of polystyrene beads and silica hybrid polymers using XPS and ToFSIMS
- XPS analysis of magnetite beads
- Investigation of the surface and depth distribution of a lubricant on drug X tablets
- Investigation of the surface composition of drug X blends and tablet cores
- Further topographical characterisation of tablet samples
- Further investigation of sulfoxide in tablets using ToF-SIMS.